We are using the site frequency spectrum to model the demographic histories of European and Asian populations.
With Dr. Kirk Lohmueller (UCLA), I am estimating demographic parameters for European and Asian populations, based on a two-dimensional site frequency spectrum (SFS) from 564 Danish and Han Chinese individuals. I am using a maximum-likelihood coalescent approach in the program fastsimcoal2 (Excoffier et al. 2013) to estimate parameters for the divergence time between the two populations, historical population sizes,bottlenecks and the timing and rates of growth.
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